Innovations in Paper/polymer Hybrid Microfluidic Devices andNanotechnology for Point-of-Care Diagnosis of Infectious Diseases

李秀军 教授

美国德克萨斯大学埃尔帕索分校

时间：2026年7月10日（星期五）15:00

地点：思明校区化学楼234会议室　　　

厦门大学谱学分析与仪器教育部重点实验室

2026年7月8日

报告人简介：

李秀军，现任美国德克萨斯大学埃尔帕索分校(University of Texas at EI Paso，缩写UTEP)终身教授和法庭科学学科主任。李秀军课题组的研究领域是面向微流控生物芯片和纳采技术在生物分析，生物医学工程，催化和环境方面的应用，特别是专注于低成本诊断、病原体和癌症标记物快速检测、纳米生物传感器，生物组织工程和单细胞分析等领域的创新和研发。他开创了纸/聚合物混合微流体生物芯片的新概念;他首次开发出使用普通温度计进行低成本定量分析的光热生物传感器。李教授在相关领域已发表高质量SCI论文130余篇(包括Adv Drug Deliv Rev, Appl Catal B-EnvironChem Sci, Anal Chem, Biosens Bioelectron),3本Elsevier专著，拥有26项专利，是生物高科技公司microBioChipDiagnostics (uBCD)的创始人. 同时还担任Nature Publishing Group的Microsystems & Nanoengineering, Scientific Reports和Micromachines等6家期刊的资深编辑，以及Lab Chip和Analyst等国际著名期刊的Advisory Board成员. 曾获得 2025 R&l Innovation Award for Establisher Innovator, 2026 NAI SeniorMember, "Bioanalysis New Investigator Award" (2014), UT STARS Award (2012), 加拿大 "NSERCPostdoctoral Fellow Award”(2009)等多项奖。详情请访问http://li.utep.edu。

报告摘要：

Infectious diseases such as COvID-19 often cause tremendous global health concerns and economicosses, necessitating simple and low-cost methods for rapid point-of -care detection of infectious diseasesin low-resource settings. Thus, we developed different low-cost paper/polymer hybrid microfluidicplatform and nano-technologies to address the increasing demand. These hybrid microfluidic systemstake advantage of both polymer and paper substrates for rapid and sensitive disease diagnosis. Fornstance, paper was used in a PDMS/ paper hybrid microfluidic system integrated with loop-mediated DNAisothermal amplification (LAMP) for rapid and sensitive multiplexed infectious disease diagnosisincluding meningitis (a global disease with high morbidity and mortality) and pertussis. The introductionof paper into the microfluidic device enables stable test results over a much longer period of time than apaper-free microfluidic system, with high detection sensitivity comparable to aPCR. Moreover, detectorree bar-chart microfluidic devices and nanomaterial-mediated photothermal biosensing using a commonthermometer will be also discussed.